{"id":247501,"date":"2024-06-14T11:47:04","date_gmt":"2024-06-14T09:47:04","guid":{"rendered":"https:\/\/invimed.pl\/?post_type=blog&#038;p=247501"},"modified":"2024-06-14T11:47:04","modified_gmt":"2024-06-14T09:47:04","slug":"what-is-progesterone-its-level-matters","status":"publish","type":"blog","link":"https:\/\/invimed.pl\/en\/blog\/czym-jest-progesteron-jego-poziom-ma-znaczenie","title":{"rendered":"What is progesterone? Its levels matter!"},"content":{"rendered":"<\/p>\n<h2>What is progesterone?<\/h2>\n<p>Progesterone is produced in the corpus luteum during the luteal phase of the menstrual cycle (the last of the&nbsp;<span style=\"font-size: 14px; letter-spacing: 0.15px;\">phases, begins after ovulation and ends just before menstruation. It usually lasts fourteen&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">days) and during pregnancy. Together with oestrogen, it is the most important female sex hormone.<\/span><\/p>\n<p>It is also produced in the adrenal cortex and testes, as well as in the placenta and central&nbsp;<span style=\"font-size: 14px; letter-spacing: 0.15px;\">nervous system. Progesterone acts on cells that have receptors&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">progesterone. Elevated or decreased progesterone can interfere with basic&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">bodily functions.<\/span><\/p>\n<\/p>\n<h2>What are the functions of progesterone?<\/h2>\n<p>Progesterone produced during the luteal phase allows implantation of the embryo in the mucosa&nbsp;<span style=\"font-size: 14px; letter-spacing: 0.15px;\">uterus. It is also responsible for the correct maintenance of pregnancy and influences cervical mucus -.&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">reduces its permeability to sperm.&nbsp;<\/span><\/p>\n<p><span style=\"font-size: 14px; letter-spacing: 0.15px;\">Decrease in progesterone levels&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">results in the exfoliation of the endometrium (menstruation). The woman then enters&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">the beginning of the follicular phase, which lasts about fourteen days (if your cycle lasts about 28 days) and&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">ends on the day of ovulation. Progesterone levels then rise, indicating the release of the&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">egg cell.&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">Progesterone in the normal range also reduces the contractility of the uterine muscle. Overall -&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">is responsible for the correct implantation of the fertilised egg cell. Its action&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">are also controlled by other hormones - mainly luteinizing hormone which is produced by the&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">pituitary gland. (1)<\/span><\/p>\n<\/p>\n<h2>Progesterone standards<\/h2>\n<p>The concentration of progesterone in women is constantly changing. It depends mainly on the phase of the cycle&nbsp;<span style=\"font-size: 14px; letter-spacing: 0.15px;\">of the menstrual cycle, i.e. the follicular, perovulatory and luteal periods. Therefore, the correct&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">progesterone levels are as follows:<\/span><\/p>\n<\/p>\n<p>    <span class=\"article__paragraph-label\">Progesterone standards in women<\/span><\/p>\n<p>\u25cf follicular phase from 0.28 to 0.72 ng\/ml;<\/p>\n<p>\u25cf perovulatory phase from 0.64 to 1.63 ng\/ml;<\/p>\n<p>\u25cf luteal phase from 4.71 to 18.0 ng\/ml.<\/p>\n<\/p>\n<p>During the last phase, the progesterone norm is significantly higher than the previous phases. During the phase&nbsp;<span style=\"font-size: 14px; letter-spacing: 0.15px;\">The luteal corpus luteum is formed in the ovary. This is when the cells of the endometrium in the&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">The woman's body accumulates nutrients that are essential for the initial&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">the period after fertilisation of the ovum and implantation of the embryo. (2)<\/span><\/p>\n<\/p>\n<h2>Progesterone below normal<\/h2>\n<p>Symptoms of low progesterone levels can include menstrual disorders, i.e. lack of&nbsp;<span style=\"font-size: 14px; letter-spacing: 0.15px;\">menstrual periods, amenorrhoea (menorrhagia) and infrequent menstruation&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">(oligomenorrhoea). Women with low progesterone levels are also more likely to find&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">painful menstruation (dysmenorhea). During dysmenorrhoea there are&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">increased blood loss of more than 80 ml or bleeding may last more than seven days.&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">Painful menstruation is characterised by excessive uterine contraction activity.&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">Women are then accompanied by severe lower abdominal pain. Infrequent menstruation is, as the&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">the name suggests, the sporadic occurrence of menstruation. The absence of menstruation, on the other hand, can be&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">also a consequence of systemic disease or dysfunction of the reproductive system. With each&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">disorder should be seen immediately by a gynaecologist. (3)&nbsp;<\/span><\/p>\n<p>Below-normal progesterone can also cause excessive hair loss and&nbsp;<span style=\"font-size: 14px; letter-spacing: 0.15px;\">dry skin.&nbsp;<\/span><strong style=\"font-size: 14px; color: rgb(72, 72, 72); letter-spacing: 0.15px;\">Low progesterone is very detrimental to women who want to get pregnant.<\/strong><\/p>\n<\/p>\n<h2>Progesterone above normal<\/h2>\n<p>Elevated progesterone levels usually manifest as swelling, varicose veins and&nbsp;<span style=\"font-size: 14px; letter-spacing: 0.15px;\">water retention in the body. This can result from various disorders, for example&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">liver failure, polycystic ovarian syndrome, adrenal-gonadal syndrome&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">and cancer of the adrenal gland or ovaries. High progesterone can also be indicative of&nbsp;<\/span><span style=\"font-size: 14px; letter-spacing: 0.15px;\">the occurrence of cysts on the ovaries.<\/span><\/p>\n<\/p>\n<h2>Progesterone standards - research<\/h2>\n<p>Progesterone testing is performed by means of a blood draw from the ulnar vein.&nbsp;<\/p>\n<\/p>\n<p>    <span class=\"article__paragraph-label\">Preparation for progesterone testing<\/span><\/p>\n<p>You should report to the collection centre on an empty stomach in the morning.&nbsp;<\/p>\n<\/p>\n<p>Furthermore, the timing of examinations in women must be correlated with medical indications and the phase of the menstrual cycle:<\/p>\n<\/p>\n<ul>\n<li>The standard progesterone norm test is performed from day 2 to day 5 of the cycle of the follicular phase;<\/li>\n<li>Ovulation monitoring is checked between days 12 and 14 of the cycle;<\/li>\n<li>The assessment of the luteal phase of the menstrual cycle is performed around day 21 of the cycle.<\/li>\n<\/ul>\n<p>Testing of the progesterone standard is reimbursed by the National Health Fund. It can also be done commercially with a charge of around 50-60 PLN. You usually wait one day for the results. Afterwards, it is essential to consult a general practitioner, who will make a diagnosis and provide appropriate treatment.<\/p>\n<\/p>\n<h3>Bibliography:<\/h3>\n<p>1. https:\/\/core.ac.uk\/download\/pdf\/268474825.pdf&nbsp;<\/p>\n<p>2.&nbsp;<span style=\"font-size: 14px; letter-spacing: 0.15px;\">http:\/\/yadda.icm.edu.pl\/baztech\/element\/bwmeta1.element.baztech-article-BPL2-0020-0043<\/span><\/p>\n<p>3. https:\/\/www.mp.pl\/pacjent\/objawy\/253859,zaburzenia-miesiaczkowania<\/p>\n<\/p>\n<h3>Authorisation of content:&nbsp;<\/h3>\n<p><strong style=\"font-size: 14px; letter-spacing: 0.15px; color: rgb(0, 0, 0);\">Dr Blanka Malczewska<\/strong><span style=\"font-size: 14px; letter-spacing: 0.15px; color: rgb(0, 0, 0);\">&nbsp;- specialist gynaecologist-obstetrician from the InviMed clinic in Gdynia&nbsp;<\/span><\/p><\/p>","protected":false},"parent":0,"menu_order":0,"template":"","blog-category":[],"blog-tags":[],"class_list":["post-247501","blog","type-blog","status-publish","hentry"],"acf":{"blog_clinics":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Czym jest progesteron? 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Progesteron powstaje w cia\u0142ku \u017c\u00f3\u0142tym w fazie lutealnej cyklu miesi\u0105czkowego (ostatnia z&nbsp;faz, rozpoczyna si\u0119 po owulacji i ko\u0144czy tu\u017c przed menstruacj\u0105. Trwa zazwyczaj czterna\u015bcie&nbsp;dni) oraz w ci\u0105\u017cy. Wraz z estrogenem, jest najwa\u017cniejszym \u017ce\u0144skim hormonem p\u0142ciowym. Produkowany jest r\u00f3wnie\u017c w korze nadnerczy i j\u0105drach, a tak\u017ce w \u0142o\u017cysku i centralnym&nbsp;uk\u0142adzie nerwowym. Progesteron [&hellip;]","og_url":"https:\/\/invimed.pl\/en\/blog\/what-is-progesterone-its-level-matters\/","og_site_name":"Invimed","twitter_card":"summary_large_image","twitter_misc":{"Estimated reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/invimed.pl\/blog\/czym-jest-progesteron-jego-poziom-ma-znaczenie","url":"https:\/\/invimed.pl\/blog\/czym-jest-progesteron-jego-poziom-ma-znaczenie","name":"What is progesterone? 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